1. Bad Project video from the Zheng lab. This is simply awesome.
2. Top 10 quirky science tricks for parties. I found out about this from Twitter ... and it is very good.
3. Cracked.Com has some funny spoofs, though usually not about science. Here is one I found about science, sort of.
Bill O'Reilly Teaches Kids About Science -- powered by Cracked.com
4. The Onion has some great science spoofs of course. I found this one but there are many more.
Brooke Alvarez Has All The Answers, Even About Particle Physics
5. Colbert has some brilliant Science spoofs. This one however takes the cake in a way: Colbert nuclear explosion
6. Robotic Operation (which I found through http://www.sciencehumor.org/category/videos/)
7. OK - so it's very very long. But there are some funny parts - the 2011 Ig Nobel Award Ceremony
8. Abby Harrison is very funny. ... I first saw here microorganism stand up stuff but I think this one is better.
9. OK so this is not the funniest video with Brian Malow but it give some background on "The Science Comedian"
10. And perhaps my favorite - from the Daily Show --- Science - What's it up to?
Please suggest others ...