Circomics was coined to describe the combination of rolling circle amplification (RCA), restriction fragment length polymorphism (RFLP) and pyro-sequencing to investigate the genome structures of small circular DNAs. A batch procedure is described using 61 plant samples from Asia, South America and Central America which revealed 83 contig sequences of geminiviral DNA components and 4 contig sequences of DNA satellites. The usefulness of this approach is validated for the Brazilian begomoviruses, and the sequence fidelity is determined by comparing the results with those of conventional cloning and sequencing of Bolivian begomoviruses reported recently. Therefore, circomics has been proven to be a major step forward to economize costs and labor and to characterize reliably geminiviral genomes in their population structure of the quasi species.This definitely fits the category of a "bad omics" word which I have history of complaining about but had been ignoring for a bit. But I am back. I am giving "Circomics" a "Worst New Omics Word Award" here because, well, it seems completely unnecessary and distracting.
Hat tip to AJ Cann for pointing this one out on Google Plus.
Almost all omics words, bad and good, refer to disciples, or subdisciplines, or at least fields of study. This one refers to a method.
ReplyDeleteAlso, I prefer my comics to be linear.