Hi - I'm Jake Scott. I met Jonathan last year when he and I spoke at TEDMED 2012. Both Jonathan and I have posted recently about the need for, and (slowly) growing movement in the biological sciences to post #preprints of manuscripts in openly accessible fora to circumvent some problems associated with standard academic publishing. Most worrisome are the issues surrounding #openaccess and the length of time it takes to get information from one's brain to the literature - drastically slowing down the pace of science.
This has worked GREAT in the physics community, where this trend really began quite some time ago when the high energy physicists started the arXiv. Now, the precedent is set, and no one in physics bats an eye about sticking their paper on the arXiv, and cite other works presented there as standard publications.
The climate in biology, sadly, is much different. Whether this is because of a more competitive climate for funding, or just a field diluted by more talented scientists, I don't know. But there is a pervasive attitude of fear and mistrust around the idea of preprints.
Before you read on (and become biased by my opinions) take a few second (really, probably 1.5 minutes) and take this quick survey:
