When I was a graduate student I was looking around for an extremophile - especially an evolutionarily novel one. And I settled on this species Haloferax volcanii - a model halophilic archaeon largely because Ford Doolittle and colleagues had started to turn it into a genetic model organism (and because Patrick Keeling, from Ford's lab convinced me it was a good thing to do). So I started work on this species - doing DNA repair studies in the lab. See my PhD thesis for some of the work I did which I never published outside of the thesis for multiple reasons. But I continued to be interested in this species. And when I was working at TIGR, an NSF Program Officer approached me asking me to help get the genome sequencing done for this species. So, well, I did: The Complete Genome Sequence of Haloferax volcanii DS2, a Model Archaeon. And I became interested in other haloarchaea and eventually started working with Marc Facciotti, in the lab next to mine, in sequencing from across the diversity of the haloarchaea: Sequencing of Seven Haloarchaeal Genomes Reveals Patterns of Genomic Flux and Phylogenetically Driven Sequencing of Extremely Halophilic Archaea Reveals Strategies for Static and Dynamic Osmo-response.
Anyway - enough about me. The whole point here is to point people to a new paper: BMC Biology | Abstract | Generation of comprehensive transposon insertion mutant library for the model archaeon, Haloferax volcanii , and its use for gene discovery. Further evidence for the use of Haloferax volcanii as a model species. Tools continue to become available for genetic and experimental studies in this species. So - if you are looking for an unusual and interesting organisms to work on - consider working on this species ...
Showing posts with label haloarchaea. Show all posts
Showing posts with label haloarchaea. Show all posts
Friday, January 02, 2015
Subscribe to:
Posts (Atom)
Most recent post
A ton to be thankful for -- here is one part of that - all the acknowledgement sections from my scholarly papers
So - it is another Thanksgiving Day and in addition to thinking about family, and football, and Alice's Restaurant, I also think a lot a...
-
Wow. Just wow. And not in a good way. Just got an email invitation to a meeting. The meeting is " THE FIRST ANNUAL WINTER Q-BIO ...
-
There is a spreading surge of PDF sharing going on in relation to a tribute to Aaron Swartz who died a few days ago. For more on Aaron ...
-
I have a hardback version of The Bird Way by Jennifer Ackerma n but had not gotten around to reading it alas. But now I am listening to th...